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There's a launch of norepinephrine from the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors while in the dorsal horn to lower afferent suffering transmission and create analgesia. For that reason, medication like clonidine that concentrate on alpha-2 receptors can affect the transmission of ache. Clonidine treats large hypertension https://peterk482egh8.eveowiki.com/user

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